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Laboratory Test Catalog

C-Reactive Protein (CRP), Synovial Fluid

This test CANNOT be ordered as a stand-alone test option.


The C-Reactive Protein (CRP) test is a quantitative in vitro laboratory developed test (LDT) to measure CRP in synovial fluid of patients experiencing pain and/or inflammation in a joint. This assay is a component of the multi-analyte diagnostic algorithm used to aid in the detection of periprosthetic joint infection (PJI). The measurement of CRP in synovial fluid is used in conjunction with other biomarkers as a component of the Synovasure® Comprehensive PJI Panel to aid the diagnosis of PJI.


Panels Included In

Synovasure® Comprehensive PJI Panel (Go to Panel)


Available in New York State?

Yes. The Synovial Fluid CRP test is available as part of the Synovasure® Comprehensive PJI Panel and Synovasure® Alpha Defensin for PJI test options.

Specimen Source(s)

Periprosthetic joint prior to implant removal

Note: Performance on specimens from other anatomic locations is not defined. Non-intraarticular joint fluid will be tested if Zimmer Biomet is participating in a clinical study.


Specimen Type

Synovial Fluid


Required Volume

1.0 mL


Volume by Tube Type*

No Additive Tube: 1.0mL

*Tubes are provided within specimen transportation kits


Specimen Stability

7 days post-aspiration


Ambient/Room Temperature prior to shipment. If being held overnight or over a weekend, store in refrigeration.


Shipping Materials

All materials needed to package and ship are included within transportation kit. Make sure to retain tracking number from provided FedEx label for tracking purposes


Shipping Guidelines

Monday to Friday

Ship specimen the same day as aspiration

Saturday to Sunday

Place in refrigeration and ship specimen on Monday

Reasons for Specimen Rejection

1.  Specimen is outside stability range

2.  Specimen is not representative of synovial fluid (i.e. blood, urine, etc.)

3.  Specimen is aspirated from a location other than the intra-articular joint space

*Note: Non-synovial fluid or intra-articular joint specimens will be tested if associated with a Zimmer Biomet-approved clinical study.

When submitting a specimen to CD Laboratories for this panel:

    • Do not use lavage, contrast or other foreign liquids to aspirate fluid
    • Ensure specimen is not overly hemolyzed
    • A completed requisition form is required with each specimen
    • A barcode label from the specimen transportation kit is required on the top of completed requisition
    • For Physician Accounts Only: Patient signature and insurance information are required


This test is not available as a stand-alone test option. For pricing for the test panels in which this test is included, please select from the below list:


CPT Codes

TestCPT Code
C-Reactive Protein, Synovial Fluid86140

Ordering SKU

This test utilizes the Infection Specimen Transportation Kit (00-8888-130-01). The test is selected using the requisition form provided within the kit as part of either the Synovasure® Comprehensive PJI Panel or Synovasure® Alpha Defensin for PJI


How to Order Kit

Contact your local Zimmer Biomet sales representative

For result or test questions, contact CD Laboratories Customer Service at 888-981-8378 or [email protected]

Download a Sample Report

Laboratory Test Catalog